Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | FCER2 | P06734 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303135 | 0.81 | MME (0.47) | MMEMMP1FCER2LTA4HANPEP | |
| SCHEMBL27477945 | 0.73 | PPARG (0.47) | MMELTA4HANPEPECE1MMP9 | |
| SCHEMBL7299652 | 0.73 | MME (0.44) | MMEMMP1FCER2LTA4HANPEP | |
| SCHEMBL7308918 | 0.73 | FCER2 (0.48) | MMEMMP1FCER2LTA4HANPEP | |
| SCHEMBL7301211 | 0.72 | MME (0.41) | MMEMMP1FCER2LTA4HANPEP | |
| SCHEMBL7306329 | 0.71 | MMP1 (0.53) | MMEMMP1FCER2MMP9MMP2 | |
| SCHEMBL7308706 | 0.71 | MMP1 (0.46) | MMEMMP1LTA4HANPEPECE1 | |
| SCHEMBL7303121 | 0.70 | MMP2 (0.60) | MMEMMP1LTA4HANPEPECE1 | |
| SCHEMBL7303711 | 0.70 | MMP2 (0.51) | MMP1MMP9MMP2MMP13MMP8 | |
| SCHEMBL27477944 | 0.68 | MME (0.42) | MMEMMP1FCER2LTA4HANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | disclosed |