Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303135 | 0.86 | MME (0.47) | MMELTA4HANPEPECE1MMP1 | |
| SCHEMBL7308706 | 0.83 | MMP1 (0.46) | MMELTA4HANPEPECE1MMP1 | |
| SCHEMBL7303121 | 0.82 | MMP2 (0.60) | MMELTA4HANPEPECE1MMP1 | |
| SCHEMBL7308918 | 0.81 | FCER2 (0.48) | MMELTA4HANPEPECE1MMP1 | |
| SCHEMBL27477944 | 0.80 | MME (0.42) | MMELTA4HANPEPECE1MMP1 | |
| SCHEMBL27477945 | 0.78 | PPARG (0.47) | MMELTA4HANPEPECE1 | |
| SCHEMBL7301205 | 0.76 | MME (0.46) | MMELTA4HANPEPECE1MMP1 | |
| SCHEMBL7303711 | 0.74 | MMP2 (0.51) | MMP1 | |
| SCHEMBL7309199 | 0.74 | NFE2L2 (0.44) | MMELTA4HANPEPECE1MMP1 | |
| SCHEMBL7306315 | 0.74 | MMP1 (0.69) | MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | disclosed |