Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | WEE1 | P30291 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301671 | 0.90 | MAT2A (0.48) | KDM4EHSD17B10MAPK1FABP4FABP5 | |
| SCHEMBL16147632 | 0.83 | FABP4 (0.61) | FABP4FABP5KMOOXER1BAZ2B | |
| SCHEMBL7653099 | 0.82 | HDAC1 (0.43) | CHEK1HDAC1HDAC8HDAC6TYMP | |
| SCHEMBL7306990 | 0.81 | KDM4E (0.49) | KDM4EHSD17B10MAPK1FABP4FABP5 | |
| SCHEMBL7300140 | 0.81 | FABP4 (0.68) | KDM4EHSD17B10MAPK1FABP4FABP5 | |
| SCHEMBL7310452 | 0.77 | ALDH1A1 (0.58) | KDM4EHSD17B10GAAHPGDALDH1A1 | |
| SCHEMBL17482044 | 0.76 | TP53 (0.53) | KDM4EHSD17B10FABP4FABP5KMO | |
| SCHEMBL1415590 | 0.75 | FABP4 (0.54) | FABP4FABP5MAPK8OXER1 | |
| SCHEMBL15286444 | 0.74 | FABP4 (0.59) | KDM4EHSD17B10MAPK1FABP4FABP5 | |
| SCHEMBL7309296 | 0.74 | TDP1 (0.47) | KDM4EHSD17B10GAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |