Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201014 | 0.91 | SMN1; SMN2 (0.41) | MMP13MMP1HPGDGAAALDH1A1 | |
| SCHEMBL7204562 | 0.90 | MMP13 (0.51) | MMP13MMP1ALDH1A1 | |
| SCHEMBL7205956 | 0.90 | MMP13 (0.53) | MMP13MMP1KMT2AMEN1 | |
| SCHEMBL7201540 | 0.89 | ADAMTS4 (0.39) | MMP13MMP1KDM4E | |
| SCHEMBL7204066 | 0.89 | ALDH1A1 (0.38) | MMP13MMP1GAAALDH1A1KMT2A | |
| SCHEMBL7203105 | 0.89 | MMP13 (0.38) | MMP13MMP1 | |
| SCHEMBL7205455 | 0.88 | MMP9 (0.44) | MMP13MMP1PKMALDH1A1KDM4E | |
| SCHEMBL7204213 | 0.86 | MMP13 (0.52) | MMP13MMP1ALDH1A1 | |
| SCHEMBL7205273 | 0.85 | MMP1 (0.56) | MMP13MMP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7202567 | 0.83 | MMP13 (0.40) | MMP13MMP1HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138680-A1 | Gem substituted sulfonyl hydroxamic acids as MMP inhibitors | Pfizer Products Inc. (US) | 2001-10-04 | — | — | EP | disclosed |