Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305895 | 0.94 | CHRM2 (0.39) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL7314354 | 0.93 | CHRM2 (0.38) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL7315123 | 0.91 | HTR7 (0.38) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL7309115 | 0.90 | HTR7 (0.38) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL7317126 | 0.89 | GRIN1 (0.42) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL7305548 | 0.89 | CHRM2 (0.39) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL7344820 | 0.88 | HRH1 (0.32) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL7309020 | 0.86 | CHRM2 (0.38) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL7307085 | 0.85 | SIGMAR1 (0.38) | HTR7CHRM2CHRM1MEN1KMT2A | |
| SCHEMBL7314634 | 0.85 | GLA (0.38) | HTR7CHRM2CHRM1GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |