Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305000 | 0.93 | CHRM2 (0.36) | HTR7SIGMAR1CHRM2CHRM1MEN1 | |
| SCHEMBL7300978 | 0.91 | HTR7 (0.39) | HTR7CHRM2CHRM1MEN1KMT2A | |
| SCHEMBL7307085 | 0.90 | SIGMAR1 (0.38) | HTR7SIGMAR1CHRM2CHRM1MEN1 | |
| SCHEMBL7305895 | 0.89 | CHRM2 (0.39) | HTR7CHRM2CHRM1TSHRMAPK1 | |
| SCHEMBL7307155 | 0.88 | ITGB3 (0.34) | HTR7CHRM2CHRM1ALOX15 | |
| SCHEMBL7316047 | 0.88 | GRIN1 (0.42) | HTR7SIGMAR1CHRM2CHRM1GRIN1 | |
| SCHEMBL7304254 | 0.85 | HRH3 (0.33) | HRH3 | |
| SCHEMBL7309115 | 0.85 | HTR7 (0.38) | HTR7SIGMAR1CHRM2CHRM1KDM4E | |
| SCHEMBL7314354 | 0.84 | CHRM2 (0.38) | HTR7CHRM2CHRM1MEN1KMT2A | |
| SCHEMBL7306204 | 0.84 | ITGB3 (0.38) | HTR7SIGMAR1CHRM2CHRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |