Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313428 | 0.93 | CYP1A2 (0.37) | HTR7KDM1ACHRM2CHRM1GRIN1 | |
| SCHEMBL7306204 | 0.91 | ITGB3 (0.38) | HTR7KDM1AKDM4EALDH1A1ALOX15 | |
| SCHEMBL7308005 | 0.91 | GLA (0.39) | GLAKDM1AKDM4EALDH1A1TP53 | |
| SCHEMBL7317126 | 0.88 | GRIN1 (0.42) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7316521 | 0.88 | SMN1; SMN2 (0.41) | HTR7KDM1AKDM4EALDH1A1GRIN2B | |
| SCHEMBL7344820 | 0.88 | HRH1 (0.32) | HTR7KDM1ACHRM2CHRM1GRIN1 | |
| SCHEMBL7300978 | 0.85 | HTR7 (0.39) | HTR7KDM4EALDH1A1CHRM2CHRM1 | |
| SCHEMBL7314354 | 0.85 | CHRM2 (0.38) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7313193 | 0.84 | SIGMAR1 (0.33) | HTR7KDM1ATRPV6HRH3 | |
| SCHEMBL7303867 | 0.84 | SMN1; SMN2 (0.38) | GLAHTR7KDM1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |