Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 6/20 | 0.40 |
| ▸ | METAP1 | P53582 | 4/20 | 0.40 |
| ▸ | REN | P00797 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303335 | 0.82 | METAP2 (0.49) | METAP2METAP1RENCTSSCTSK | |
| SCHEMBL10346884 | 0.80 | REN (0.39) | METAP2METAP1RENCTSSCTSK | |
| SCHEMBL10520251 | 0.79 | REN (0.41) | METAP2METAP1RENCTSSCTSK | |
| SCHEMBL10445626 | 0.77 | METAP2 (0.52) | METAP2METAP1CTSSCTSK | |
| SCHEMBL7429150 | 0.77 | CTSK (0.44) | METAP2METAP1RENCTSSCTSK | |
| SCHEMBL20244849 | 0.76 | CTSK (0.45) | METAP2CTSSCTSK | |
| SCHEMBL22090642 | 0.76 | CTSK (0.45) | METAP2CTSSCTSK | |
| SCHEMBL7436405 | 0.76 | REN (0.42) | METAP2METAP1REN | |
| SCHEMBL10521580 | 0.75 | METAP2 (0.37) | METAP2METAP1RENCTSSCTSK | |
| SCHEMBL7294534 | 0.75 | CTSL (0.47) | METAP2METAP1RENCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368719-B1 | Novel analogs of peptidase substrates | MERRELL PHARMA INC (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0371179-A1 | Novel analogs of peptidase substrates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0368719-A2 | Novel analogs of peptidase substrates | MERRELL PHARMACEUTICALS INC. (US) | 1990-05-16 | — | — | EP | disclosed |