Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304463 | 0.92 | CYP1A2 (0.43) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL7313561 | 0.85 | CTSK (0.47) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL7306604 | 0.84 | MAPT (0.46) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL7313867 | 0.82 | CTSK (0.48) | CTSKCTSSCTSLCTSBCXCR3 | |
| SCHEMBL7314443 | 0.82 | CTSK (0.48) | CTSKCTSSCTSLCTSBCXCR3 | |
| SCHEMBL7305458 | 0.82 | CTSK (0.46) | CTSKCTSSMAPTMEN1KMT2A | |
| SCHEMBL7317918 | 0.75 | CTSK (0.46) | CTSKCTSSMAPTMEN1KMT2A | |
| SCHEMBL10630212 | 0.75 | CTSK (0.57) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL8083546 | 0.74 | ERAP2 (0.45) | CTSKCTSSCTSLALDH1A1MMP9 | |
| SCHEMBL7834971 | 0.74 | CTSK (0.55) | CTSKCTSSCTSLCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |