Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314443 | 0.87 | CTSK (0.48) | CTSKCTSSATMCXCR3CTSL | |
| SCHEMBL7313867 | 0.87 | CTSK (0.48) | CTSKCTSSATMCXCR3CTSL | |
| SCHEMBL7301520 | 0.85 | CTSK (0.44) | CTSKCTSSALDH1A1CXCR3CTSL | |
| SCHEMBL6862901 | 0.81 | ALDH1A1 (0.51) | CTSKCTSSKDM4EALDH1A1HTT | |
| SCHEMBL8083658 | 0.81 | CTSK (0.46) | CTSKCTSSALDH1A1CTSLCTSB | |
| SCHEMBL7305458 | 0.79 | CTSK (0.46) | CTSKCTSSKDM4EALDH1A1MAPT | |
| SCHEMBL11899346 | 0.78 | CA1 (0.39) | CTSKCTSSCTSLCTSBCA12 | |
| SCHEMBL7834971 | 0.78 | CTSK (0.55) | CTSKCTSSATMCXCR3CTSL | |
| SCHEMBL9230376 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1HTTSMN1; SMN2CA12 | |
| SCHEMBL9228418 | 0.77 | MTNR1A (0.45) | CTSKCTSSALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |