Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825414 | 0.86 | LMNA (0.63) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL27620333 | 0.86 | KDM4E (0.54) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL5190596 | 0.86 | CTSS (0.59) | LMNATSHRMEN1KMT2ATDP1 | |
| SCHEMBL11378089 | 0.86 | LMNA (0.55) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL7397340 | 0.84 | LMNA (0.57) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL6314244 | 0.84 | LMNA (0.49) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL6314236 | 0.84 | LMNA (0.49) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL638764 | 0.84 | LMNA (0.61) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL8718249 | 0.84 | LMNA (0.61) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL673623 | 0.84 | LMNA (0.61) | LMNAALDH1A1NPSR1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045513-B2 | Method for preparing precursor used for labeling hepatocyte receptor and containing trisaccharide and DTPA ligand | Atomic Energy Council—Institute of Nuclear Energy Research (TW) | 2015-06-02 | — | — | US | disclosed |
| US-20140046045-A1 | METHOD FOR PREPARING PRECURSOR USED FOR LABELING HEPATOCYTE RECEPTOR AND CONTAINING TRISACCHARIDE AND DTPA LIGAND | ATOMIC ENERGY COUNCIL - INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2014-02-13 | — | — | US | disclosed |
| CN-102532127-A | Improved method for synthetizing novel P38 mitogen-activated protein kinase inhibitor | SHANGHAI AINAKE BIOMEDICINE TECHNOLOGY CO LTD | 2012-07-04 | — | — | CN | disclosed |
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6458959-B1 | VIRICIDES AND ENZYME INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6348477-B1 | SUBSTITUTED PHENYL THIAZOLE DERIVATIVES AS VIRICIDES | BOEHRINGER INGELHEIM(CANADA) LTD. (CA) | 2002-02-19 | — | — | US | disclosed |
| US-6288091-B1 | COMPOUNDS SUCH AS 2,2,2-TRICHLOROETHYL N-(4-(2-AMINO-4-THIAZOLYL)-PHENYL)CARBAMATE THAT INHIBIT THE HERPES HELCASE-PRIMASE ENZYME COMPLEX | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-11 | — | — | US | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |
| US-5428009-A | Antibiotics, fungicides, and antiprotozoa agents | MERCK & CO., INC. (US) | 1995-06-27 | — | — | US | disclosed |
| US-5385884-A | Water-soluble, injectible echinocandins; fungicides; antiprotozoa agents, yeasts | MERCK & CO. INC. (US) | 1995-01-31 | — | — | US | disclosed |
| US-5369093-A | Antibiotic lipopeptides as fungicides and antiprotozoa agents | MERCK & CO., INC. (US) | 1994-11-29 | — | — | US | disclosed |
| US-5330973-A | Fungicides, antiprotozoa agents | MERCK & CO., INC. (US) | 1994-07-19 | — | — | US | disclosed |
| EP-0503960-A1 | Cyclic lipopeptides having antibiotic activity | MERCK & CO. INC. (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0448354-A2 | Lipopeptide derivatives | MERCK & CO. INC. (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0448343-A2 | Lipopeptide derivatives | MERCK & CO. INC. (US) | 1991-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046045-A1 | METHOD FOR PREPARING PRECURSOR USED FOR LABELING HEPATOCYTE RECEPTOR AND CONTAINING TRISACCHARIDE AND DTPA LIGAND | HDGF, NR1H4, TRHR | LMNA 2172/4885ALDH1A1 4339/4885NPSR1 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.