Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 3/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651696 | 0.88 | MAT2A (0.44) | MAT2ATYMPHTR7 | |
| SCHEMBL7309368 | 0.88 | MAT2A (0.44) | MAT2ATYMP | |
| SCHEMBL7301671 | 0.83 | MAT2A (0.48) | MAT2ATYMP | |
| SCHEMBL7305582 | 0.81 | HTR1A (0.50) | TYMPHTR7PARP1HTR1A | |
| SCHEMBL7649804 | 0.80 | HTR1A (0.49) | TYMPHTR7PARP1HTR1A | |
| SCHEMBL318631 | 0.80 | DAO (0.55) | HTR7PGRHTR1A | |
| SCHEMBL7309296 | 0.77 | TDP1 (0.47) | MAT2A | |
| SCHEMBL7312723 | 0.77 | HTR1A (0.57) | HTR7HTR1A | |
| SCHEMBL7653099 | 0.77 | HDAC1 (0.43) | TYMP | |
| SCHEMBL446902 | 0.77 | PARP1 (0.50) | PARP1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |