SCHEMBL730270

SCHEMBL730270

CCOC(=O)C(CC(=O)O)NC[SiH2]OC(C)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
HTT P42858 1/20 0.30
CAD P27708 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728609 0.89 L3MBTL1 (0.35) CYP1A2CYP2C9CYP2C19HTTCAD
SCHEMBL728608 0.85 MAPT (0.32)
SCHEMBL728351 0.80 CTSK (0.33)
SCHEMBL27400849 0.70 CAD (0.38) EGLN1CYP1A2CYP2C9CYP2C19HTT
SCHEMBL27400855 0.70 CAD (0.38) EGLN1CYP1A2CYP2C9CYP2C19HTT
SCHEMBL15636484 0.69 TDP1 (0.36) EGLN1CADL3MBTL1
SCHEMBL730224 0.68 L3MBTL1 (0.37) EGLN1CADL3MBTL1
SCHEMBL28215680 0.67 GGT1 (0.40) CYP1A2CADL3MBTL1
SCHEMBL14951131 0.67 CAD (0.41) EGLN1CADL3MBTL1
SCHEMBL22111291 0.67 CAD (0.41) EGLN1CADL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed