Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.64 |
| ▸ | DRD2 | P14416 | 5/20 | 0.64 |
| ▸ | HTR2A | P28223 | 4/20 | 0.64 |
| ▸ | HTR7 | P34969 | 12/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303413 | 0.85 | MAPT (0.49) | HTR1ADRD2HTR2A | |
| SCHEMBL7306583 | 0.84 | HTR1A (0.70) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL7297796 | 0.83 | HTR1A (0.68) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7299129 | 0.83 | HTR1A (0.68) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7300518 | 0.80 | HTR7 (0.77) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL7297432 | 0.80 | HTR7 (0.74) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL7301822 | 0.79 | HTR1A (0.63) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7305169 | 0.77 | HTR1A (0.61) | HTR1ADRD2HTR2AHTR7DRD3 | |
| SCHEMBL23536279 | 0.76 | HTR1A (0.58) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL29932017 | 0.76 | HTR1A (0.58) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |