Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.38 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.38 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.38 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.38 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296817 | 0.91 | MAPT (0.44) | ITGB3ITGA2BMMP1PRSS1CCKBR | |
| Iodide SCHEMBL9221941 | 0.90 | CCKBR (0.43) | ITGB3ITGA2BMMP1PRSS1CCKBR | |
| SCHEMBL9224835 | 0.87 | ABCB1 (0.42) | ITGB3ITGA2BABCB1MMP1PRSS1 | |
| Iodide SCHEMBL9217545 | 0.84 | CCKBR (0.42) | ITGB3ITGA2BMMP1CCKBRTMPRSS11D | |
| SCHEMBL7302254 | 0.83 | TDP1 (0.46) | MMP1CCKBR | |
| SCHEMBL7298759 | 0.82 | ITGB3 (0.40) | ITGB3ITGA2BPRSS1TMPRSS11D | |
| Iodide SCHEMBL9223883 | 0.82 | CCKBR (0.43) | ADCY6ADCY3ADCY9ADCY5ADCY8 | |
| SCHEMBL7336100 | 0.81 | CTSL (0.49) | ITGB3ITGA2BABCB1CCKBR | |
| SCHEMBL9218412 | 0.79 | ST14 (0.47) | ITGB3ITGA2BMMP1PRSS1TMPRSS15 | |
| SCHEMBL7301659 | 0.79 | CTSG (0.46) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |