Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273654 | 0.91 | SIGMAR1 (0.44) | SIGMAR1OPRM1OPRD1CHRM4FAAH | |
| SCHEMBL7280539 | 0.84 | SIGMAR1 (0.44) | SIGMAR1FAAHDRD2DRD3 | |
| SCHEMBL7275568 | 0.84 | SIGMAR1 (0.46) | SIGMAR1DRD2ALDH1A1DRD3CHRNB4 | |
| SCHEMBL7281972 | 0.83 | SIGMAR1 (0.43) | SIGMAR1FAAHMGLLLMNAHDAC3 | |
| SCHEMBL7272709 | 0.83 | SIGMAR1 (0.38) | SIGMAR1OPRM1DRD2DRD3NR1H2 | |
| SCHEMBL7276136 | 0.83 | SIGMAR1 (0.40) | SIGMAR1OPRM1KDM4EPKMDRD2 | |
| SCHEMBL7283282 | 0.82 | KDM4E (0.41) | SIGMAR1KDM4EPKMDRD2NR1H2 | |
| SCHEMBL7275535 | 0.82 | CCR3 (0.43) | SIGMAR1OPRM1OPRD1CHRM4LMNA | |
| SCHEMBL7282148 | 0.81 | SIGMAR1 (0.43) | SIGMAR1FAAHMGLLLMNAHDAC3 | |
| SCHEMBL7274528 | 0.81 | SIGMAR1 (0.45) | SIGMAR1OPRM1OPRD1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |