Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPA2 | P48052 | 1/20 | 0.36 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348935 | 0.92 | ALDH1A1 (0.41) | PSMB5PSMB1PSMB2CTSLPOLB | |
| SCHEMBL7348931 | 0.92 | ALDH1A1 (0.41) | PSMB5PSMB1PSMB2CTSLPOLB | |
| SCHEMBL7434956 | 0.88 | MMP3 (0.36) | PSMB5PSMB1PSMB2CTSLMMP8 | |
| SCHEMBL7305254 | 0.87 | PSMB5 (0.39) | PSMB5PSMB1PSMB2CTSLMMP8 | |
| SCHEMBL7305250 | 0.84 | TAS1R3 (0.52) | PSMB5PSMB1PSMB2CTSL | |
| SCHEMBL7307336 | 0.83 | PSMB5 (0.47) | PSMB5PSMB1PSMB2MMP8 | |
| SCHEMBL7300556 | 0.83 | PSMB5 (0.60) | PSMB5PSMB1PSMB2MMP8FCER2 | |
| SCHEMBL7300546 | 0.83 | PSMB5 (0.60) | PSMB5PSMB1PSMB2MMP8FCER2 | |
| SCHEMBL7300785 | 0.83 | REN (0.51) | PSMB5PSMB1PSMB2 | |
| SCHEMBL7300779 | 0.83 | REN (0.51) | PSMB5PSMB1PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0525420-A1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | Mitsubishi Chemical Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |