Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764115 | 0.92 | GGT1 (0.52) | CA1ANPEPFNTAFNTBGGT1 | |
| Hydrochloric Acid SCHEMBL11094927 | 0.91 | GGT1 (0.51) | CA1ANPEPFNTAFNTBGGT1 | |
| SCHEMBL7265651 | 0.86 | ANPEP (0.55) | ANPEPLTA4HGAA | |
| SCHEMBL30882671 | 0.85 | OPRK1 (0.49) | ANPEPCA2OPRK1GAAGGT1 | |
| SCHEMBL30882505 | 0.85 | OPRK1 (0.49) | ANPEPCA2OPRK1GAAGGT1 | |
| SCHEMBL8936109 | 0.85 | CA1 (0.57) | CA1ANPEPLTA4HFNTAFNTB | |
| Hydrochloric Acid SCHEMBL30882685 | 0.84 | OPRK1 (0.48) | ANPEPCA2OPRK1GAAGGT1 | |
| SCHEMBL7305459 | 0.83 | MTNR1A (0.48) | ANPEPFNTAFNTBOPRK1GAA | |
| SCHEMBL8615415 | 0.82 | CTSK (0.53) | OPRK1GGT1 | |
| SCHEMBL2246535 | 0.81 | KEAP1 (0.49) | GGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |