Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305924 | 0.76 | CTSK (0.43) | MEN1KMT2ANPSR1MMP9MMP13 | |
| SCHEMBL7305247 | 0.75 | MMP9 (0.70) | MMP9MMP13MMP1MMP2SMN1; SMN2 | |
| SCHEMBL7310802 | 0.73 | MMP2 (0.41) | MEN1KMT2ANPSR1MMP9MMP13 | |
| SCHEMBL7302689 | 0.72 | MMP9 (0.74) | MMP9MMP13MMP1SCN9AMMP2 | |
| SCHEMBL7302697 | 0.72 | MMP9 (0.74) | MMP9MMP13MMP1SCN9AMMP2 | |
| SCHEMBL31544498 | 0.65 | SMN1; SMN2 (0.53) | MMP9MMP13MMP1ALDH1A1MMP2 | |
| SCHEMBL24283531 | 0.63 | SMN1; SMN2 (0.58) | FNTAFNTBALDH1A1SMN1; SMN2MAPK1 | |
| Anisole SCHEMBL6951633 | 0.63 | CA4 (0.64) | KMT2ANPSR1ALDH1A1SMN1; SMN2MAPK1 | |
| Anisole SCHEMBL28158707 | 0.63 | CA4 (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28963089 | 0.63 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |