Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313519 | 0.91 | SMN1; SMN2 (0.40) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7315328 | 0.89 | CHRM4 (0.32) | ALDH1A1ITGB3ITGA2BCHRM4 | |
| SCHEMBL7317052 | 0.89 | SMN1; SMN2 (0.34) | OPRL1LMNAOPRM1CHRM4MEN1 | |
| SCHEMBL7311499 | 0.85 | ACHE (0.42) | ALDH1A1CHRM4GAA | |
| SCHEMBL7310453 | 0.84 | OPRL1 (0.34) | OPRL1ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7310996 | 0.83 | PKM (0.33) | OPRM1CHRM4 | |
| SCHEMBL7305967 | 0.81 | KDM1A (0.34) | ALDH1A1KDM4EOPRM1CHRM4MEN1 | |
| SCHEMBL7305758 | 0.79 | SIGMAR1 (0.36) | — | |
| SCHEMBL7313193 | 0.78 | SIGMAR1 (0.33) | OPRL1OPRM1 | |
| SCHEMBL7313690 | 0.78 | CYP1A2 (0.33) | ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |