Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310996 | 0.89 | PKM (0.33) | CHRM4GSK3B | |
| SCHEMBL7306388 | 0.89 | OPRL1 (0.32) | CHRM4ALDH1A1ITGB3ITGA2B | |
| SCHEMBL7305967 | 0.87 | KDM1A (0.34) | CHRM4GSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL7316859 | 0.86 | ACHE (0.43) | SMN1; SMN2 | |
| SCHEMBL7313581 | 0.83 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL7313519 | 0.82 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7317052 | 0.81 | SMN1; SMN2 (0.34) | CHRM4SMN1; SMN2 | |
| SCHEMBL7319402 | 0.78 | SIGMAR1 (0.35) | CHRM4 | |
| SCHEMBL7306204 | 0.77 | ITGB3 (0.38) | ALDH1A1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL7311499 | 0.77 | ACHE (0.42) | CHRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |