Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPD | P32754 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317786 | 0.85 | ALDH1A1 (0.38) | LMNAMAPTL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL7315902 | 0.84 | HTR7 (0.34) | LMNAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7317266 | 0.83 | PDE3B (0.48) | SMN1; SMN2KDM4EALDH1A1KMT2ACYP2C19 | |
| SCHEMBL10376782 | 0.78 | PDE3B (0.40) | MAPTL3MBTL1HPDHTR1AHTR1D | |
| SCHEMBL7312011 | 0.77 | CASP6 (0.38) | LMNAMAPTL3MBTL1SMN1; SMN2HPD | |
| SCHEMBL10908860 | 0.75 | POLB (0.47) | LMNAMAPTL3MBTL1SMN1; SMN2HPD | |
| SCHEMBL7319242 | 0.74 | LMNA (0.40) | LMNAMAPTL3MBTL1SMN1; SMN2HPD | |
| SCHEMBL7318852 | 0.73 | CASP6 (0.36) | LMNAMAPTL3MBTL1SMN1; SMN2HPD | |
| SCHEMBL4869351 | 0.69 | TDP1 (0.50) | LMNAMAPTL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL7309666 | 0.69 | KDM4E (0.38) | LMNAMAPTL3MBTL1SMN1; SMN2HPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |