Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306586 | 0.84 | LMNA (0.37) | HTR7HTR1DHTR2BALDH1A1LMNA | |
| SCHEMBL7311484 | 0.83 | PDE3B (0.47) | ALDH1A1KMT2AMEN1KDM4ECYP2C19 | |
| SCHEMBL7317786 | 0.83 | ALDH1A1 (0.38) | ALDH1A1LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL10374675 | 0.81 | PDE3B (0.39) | HTR7HTR1DHTR2BALDH1A1LMNA | |
| SCHEMBL10374677 | 0.79 | PDE3B (0.39) | HTR7HTR1DHTR2BL3MBTL1KMT2A | |
| SCHEMBL7318978 | 0.76 | PPARG (0.39) | ALDH1A1LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL7314747 | 0.76 | SIGMAR1 (0.38) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL7303043 | 0.75 | CASP6 (0.35) | L3MBTL1 | |
| SCHEMBL7303038 | 0.73 | PDE3B (0.36) | HTR7HTR1DHTR2BL3MBTL1KMT2A | |
| SCHEMBL7314783 | 0.73 | CASP6 (0.35) | ALDH1A1LMNAL3MBTL1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |