Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303299 | 0.78 | CTSS (0.48) | ADRB2ADRB1ADRB3NR1D1TDP1 | |
| SCHEMBL25387998 | 0.76 | HPGD (0.53) | ADRB2ADRB1ADRB3ALDH1A1HPGD | |
| SCHEMBL6447173 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EMEN1MAPK1 | |
| SCHEMBL26270328 | 0.74 | PLK1 (0.54) | ALDH1A1HPGDMEN1KMT2APLK1 | |
| SCHEMBL974720 | 0.74 | NR4A1 (0.53) | ADRB2ADRB1ADRB3ALDH1A1HPGD | |
| SCHEMBL10389722 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMAPK1TDP1 | |
| SCHEMBL7286194 | 0.73 | CDYL (0.56) | NR1D1KDM4ETDP1CYP1A2L3MBTL1 | |
| SCHEMBL6446932 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EMEN1MAPK1 | |
| SCHEMBL6446931 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EMEN1MAPK1 | |
| SCHEMBL7295906 | 0.71 | CDC25B (0.56) | ADRB2ADRB1ADRB3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |