Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286194 | 0.81 | CDYL (0.56) | CTSSCTSKL3MBTL1NR1D1TDP1 | |
| SCHEMBL7307013 | 0.78 | ADRB2 (0.44) | CTSSCTSKL3MBTL1NR1D1TDP1 | |
| SCHEMBL2914936 | 0.78 | SIRT5 (0.59) | CTSSCTSKL3MBTL1NR1D1TDP1 | |
| SCHEMBL9740320 | 0.77 | CTSS (0.51) | CTSSCTSKCTNNB1L3MBTL1NR1D1 | |
| SCHEMBL27647716 | 0.76 | CTSS (0.52) | CTSSCTSKCTNNB1L3MBTL1TDP1 | |
| SCHEMBL2366865 | 0.75 | CDYL (0.48) | CTSSCTSKL3MBTL1NR1D1TDP1 | |
| SCHEMBL27563011 | 0.75 | CTSS (0.57) | CTSSCTSKCTNNB1L3MBTL1NR1D1 | |
| SCHEMBL6318009 | 0.75 | CTSS (0.57) | CTSSCTSKCTNNB1L3MBTL1NR1D1 | |
| SCHEMBL7311918 | 0.75 | CTSS (0.51) | CTSSCTSKCTNNB1L3MBTL1TDP1 | |
| SCHEMBL13575223 | 0.75 | CTSS (0.51) | CTSSCTSKCTNNB1L3MBTL1NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |