Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300179 | 0.84 | KDM5B (0.45) | FOLH1MMEECE1KDM4CKDM5B | |
| SCHEMBL10778660 | 0.80 | MME (0.51) | FOLH1MMEECE1 | |
| SCHEMBL7297368 | 0.78 | KDM5A (0.44) | KDM5AKDM4CKDM5B | |
| SCHEMBL7307415 | 0.76 | KDM5A (0.40) | KDM5AKDM4CKDM5B | |
| SCHEMBL7303824 | 0.73 | LNPEP (0.43) | KDM5AKDM4CKDM5B | |
| SCHEMBL10779210 | 0.73 | CYP1A2 (0.49) | FOLH1MMEKDM4CKDM5B | |
| SCHEMBL7303694 | 0.72 | LNPEP (0.57) | KDM4CKDM5B | |
| Hydrochloric Acid SCHEMBL7303882 | 0.71 | LNPEP (0.56) | KDM5B | |
| SCHEMBL7301489 | 0.70 | MME (0.60) | MME | |
| SCHEMBL7306530 | 0.69 | LNPEP (0.45) | KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636630-B1 | N-heteroaryl substituted derivatives of propanamide useful in the treatment of cardiovascular diseases | ZAMBON SPA (IT) | 1999-04-28 | — | — | EP | disclosed |
| US-5438046-A | Enzyme inhibitors | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | disclosed |
| EP-0636630-A1 | N-heteroaryl substituted derivatives of propanamide useful in the treatment of cardiovascular diseases | ZAMBON GROUP S.p.A. (IT) | 1995-02-01 | — | — | EP | disclosed |