Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 4/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306530 | 0.91 | LNPEP (0.45) | LNPEPIL1RNKDM5BMAPTGSK3B | |
| SCHEMBL7297368 | 0.86 | KDM5A (0.44) | KDM5AKDM5BKDM4CMAPTGSK3B | |
| SCHEMBL7269082 | 0.75 | GPR132 (0.49) | GPR132TACR1 | |
| SCHEMBL7269089 | 0.75 | GPR132 (0.49) | GPR132TACR1 | |
| SCHEMBL10778660 | 0.74 | MME (0.51) | MAPTALDH1A1 | |
| SCHEMBL7307409 | 0.73 | LAP3 (0.42) | KDM5AKDM5BKDM4C | |
| SCHEMBL7295772 | 0.73 | TACR1 (0.54) | ALDH1A1TACR1 | |
| Lithium Ion SCHEMBL7297039 | 0.73 | KDM4A (0.41) | IL1RNKDM5BKDM4CMAPTGSK3B | |
| SCHEMBL9244629 | 0.72 | LNPEP (0.42) | LNPEPIL1RNKDM5BKDM4CMAPT | |
| SCHEMBL7301392 | 0.72 | KDM5B (0.42) | LNPEPIL1RNKDM5BGPR132MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636630-B1 | N-heteroaryl substituted derivatives of propanamide useful in the treatment of cardiovascular diseases | ZAMBON SPA (IT) | 1999-04-28 | — | — | EP | disclosed |
| US-5438046-A | Enzyme inhibitors | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | disclosed |
| EP-0636630-A1 | N-heteroaryl substituted derivatives of propanamide useful in the treatment of cardiovascular diseases | ZAMBON GROUP S.p.A. (IT) | 1995-02-01 | — | — | EP | disclosed |