Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16368530 | 0.83 | CYP19A1 (0.56) | CYP19A1FFAR1ESR2GABRG2GABRB3 | |
| SCHEMBL8486934 | 0.83 | TRPA1 (0.49) | CYP19A1FFAR1ESR2GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL16343426 | 0.82 | CYP19A1 (0.54) | CYP19A1FFAR1ESR2GABRG2GABRB3 | |
| SCHEMBL31772593 | 0.81 | ESR2 (0.59) | CYP19A1FFAR1ESR2GABRG2GABRB3 | |
| SCHEMBL357 | 0.81 | ESR2 (0.59) | CYP19A1FFAR1ESR2GABRG2GABRB3 | |
| SCHEMBL7795534 | 0.79 | ESR2 (0.41) | CYP19A1FFAR1ESR2GABRG2GABRB3 | |
| SCHEMBL1373278 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10MEN1MAPK1 | |
| SCHEMBL1838707 | 0.78 | CYP19A1 (0.55) | CYP19A1ESR2GABRG2GABRB3GABRA5 | |
| SCHEMBL8155256 | 0.78 | CYP19A1 (0.55) | CYP19A1ESR2GABRG2GABRB3GABRA5 | |
| SCHEMBL27895577 | 0.78 | ESR2 (0.69) | CYP19A1FFAR1ESR2GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497300-C | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1537105-A | Quinazolines useful as MMP-13 inhibitors | ��������ʲ��������ι�˾ | 2004-10-13 | — | — | CN | disclosed |
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
| CN-1058966-C | Producing process for crystal of 2-oxyethyl-1-[2'-(1H-tetrazole-5-radical)diphenyl-4-(methyl)benzimidazole-7-hydroxy acid 1-(cyclohexyloxy) ethyl ester | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-11-29 | — | — | CN | disclosed |
| CN-1048486-C | Benzimidazole derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-01-19 | — | — | CN | disclosed |
| CN-1203223-A | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-12-30 | — | — | CN | disclosed |
| CN-1147515-A | Producing process for crystal of 2-oxyethyl-1-[2'-(1H-tetrazole-5-radical)diphenyl-4-(methyl)benzimidazole-7-hydroxy acid 1-(cyclohexyloxy) ethyl ester | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-04-16 | — | — | CN | disclosed |
| CN-1025331-C | Biphenylmethane derivative and pharmacological use | EISAI CO LTD (JP) | 1994-07-06 | — | — | CN | disclosed |
| CN-1055927-A | Benzimidazole derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-11-06 | — | — | CN | disclosed |
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |
| CN-1050539-A | Diphenyl methane derivative and medicinal | EISAI CO LTD (JP) | 1991-04-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | CYP19A1 4833/4885FFAR1 4207/4885ESR2 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.