Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307705 | 1.00 | ATM (0.42) | ATMALDH1A1HPGDCTSSTSHR | |
| SCHEMBL9740119 | 0.77 | USP30 (0.44) | ATMHPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL7315141 | 0.77 | RAB9A (0.44) | ATMALDH1A1HPGDCTSSTSHR | |
| SCHEMBL7315133 | 0.77 | RAB9A (0.44) | ATMALDH1A1HPGDCTSSTSHR | |
| SCHEMBL7268082 | 0.72 | CTSS (0.51) | ALDH1A1HPGDCTSSL3MBTL1CTSL | |
| SCHEMBL7275086 | 0.72 | CTSS (0.51) | ALDH1A1HPGDCTSSL3MBTL1CTSL | |
| SCHEMBL7301956 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRLMNANPSR1 | |
| SCHEMBL7301964 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRLMNANPSR1 | |
| SCHEMBL7312766 | 0.69 | ALDH1A1 (0.50) | ATMALDH1A1HPGDCTSSL3MBTL1 | |
| SCHEMBL7360069 | 0.68 | ATM (0.39) | ATMALDH1A1CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0473936-A1 | Renin Inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |