SCHEMBL7307869

SCHEMBL7307869

CCn1cc(CCNC(=O)OC(C)(C)C)c2cc(-c3cccc4c3oc3ccccc34)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.40
BCHE P06276 1/20 0.40
POLB P06746 1/20 0.40
NQO2 P16083 1/20 0.40
ALOX5 P09917 1/20 0.39
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
TP53 P04637 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
GGPS1 O95749 1/20 0.37
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
CNR1 P21554 1/20 0.35
BRD4 O60885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7311385 0.85 HTR6 (0.44) CNR2BCHENQO2MEN1KMT2A
SCHEMBL7307874 0.82 ALOX5 (0.39) CNR2BCHEALOX5GGPS1ICMT
SCHEMBL7451295 0.81 HTR6 (0.35) CAMK2D
SCHEMBL14550793 0.79 HDAC10 (0.53) POLBNQO2MEN1KMT2ATP53
Hydrochloric Acid SCHEMBL7311209 0.79 ALOX5 (0.45) POLBALOX5GGPS1ICMTPRKDC
SCHEMBL7319201 0.74 CNR2 (0.42) CNR2ALOX5GGPS1ICMTCAMK2D
SCHEMBL7312113 0.74 MTNR1A (0.46) NQO2MEN1KMT2AHDAC10HDAC6
SCHEMBL7314789 0.73 CNR1 (0.41) CNR2POLBALOX5GGPS1CNR1
SCHEMBL9448771 0.73 KDM4E (0.44) POLBNQO2MEN1KMT2ATP53
Hydrochloric Acid SCHEMBL7311237 0.73 ALOX5 (0.45) ALOX5GGPS1ICMTPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004198-A1 Novel anti-infectives SMITHKLINE BEECHAM CORPORATION 2002-01-10 US disclosed
US-20010007877-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION 2001-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010007877-A1 NOVEL ANTI-INFECTIVES CTSL, MMP8, SERPINB1 CNR2 4068/4885BCHE 3267/4885POLB 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.