Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314659 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KDM4EACHESMN1; SMN2RECQL | |
| SCHEMBL7305616 | 0.91 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EACHESMN1; SMN2RECQL | |
| SCHEMBL7306453 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EACHESMN1; SMN2RECQL | |
| SCHEMBL7305780 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EACHESMN1; SMN2RECQL | |
| SCHEMBL7311499 | 0.85 | ACHE (0.42) | ALDH1A1ACHECHRM4TSHRFAAH | |
| SCHEMBL7306412 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EACHESMN1; SMN2RECQL | |
| SCHEMBL7304933 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4EACHESMN1; SMN2RECQL | |
| SCHEMBL7307905 | 0.84 | FKBP1A (0.32) | SMN1; SMN2RECQLOPRM1OPRL1FKBP1A | |
| SCHEMBL7305487 | 0.83 | ALDH1A1 (0.42) | ALDH1A1ACHESMN1; SMN2KMT2AOPRL1 | |
| SCHEMBL7309154 | 0.83 | ACHE (0.45) | ACHECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |