Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303908 | 0.92 | REN (0.49) | RENCTSLCASP3CTSBCTSK | |
| SCHEMBL7307293 | 0.91 | CTSS (0.44) | RENCTSSCTSKCTSE | |
| SCHEMBL10718613 | 0.87 | CTSL (0.45) | RENCTSLCASP3CTSSCTSB | |
| SCHEMBL10718460 | 0.84 | REN (0.47) | RENCTSLCASP3CTSSCTSB | |
| SCHEMBL10716091 | 0.84 | REN (0.44) | RENCTSLCASP3CTSSCTSB | |
| SCHEMBL7283203 | 0.84 | CTSL (0.43) | RENCTSLCASP3CTSSCTSB | |
| SCHEMBL7274969 | 0.83 | CTSL (0.45) | RENCTSLCASP3CTSSCTSB | |
| SCHEMBL7277678 | 0.83 | MME (0.48) | CTSLMMEECE1 | |
| SCHEMBL10762553 | 0.82 | CTSL (0.45) | RENCTSLCASP3CTSSCTSB | |
| SCHEMBL10715808 | 0.82 | CTSL (0.44) | RENCTSLCASP3CTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |