Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308672 | 0.92 | REN (0.46) | RENCTSLCTSBCTSKCASP3 | |
| SCHEMBL10718613 | 0.86 | CTSL (0.45) | RENCTSLCTSBCTSKCASP3 | |
| SCHEMBL10718705 | 0.84 | REN (0.46) | RENCTSLCTSBCTSKANPEP | |
| SCHEMBL10718460 | 0.84 | REN (0.47) | RENCTSLCTSBCTSKANPEP | |
| SCHEMBL7286158 | 0.84 | MMP2 (0.48) | RENCTSLCTSBCTSKANPEP | |
| SCHEMBL7283203 | 0.83 | CTSL (0.43) | RENCTSLCTSBCASP3 | |
| SCHEMBL10716091 | 0.83 | REN (0.44) | RENCTSLCTSBCTSKCASP3 | |
| SCHEMBL7274934 | 0.83 | REN (0.45) | RENCTSLCTSBCTSKANPEP | |
| SCHEMBL7307293 | 0.82 | CTSS (0.44) | RENCTSK | |
| SCHEMBL10762553 | 0.82 | CTSL (0.45) | RENCTSLCTSBCTSKCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |