Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308113 | 0.73 | SIGMAR1 (0.41) | KDM4EPOLBMAPK1SMN1; SMN2CNR1 | |
| SCHEMBL23647320 | 0.70 | CASR (0.46) | TDP1KDM4EGAAMAPTPKM | |
| SCHEMBL7304554 | 0.70 | ALDH1A1 (0.42) | KDM4EMAPTPKMAPOBEC3GMAPK1 | |
| SCHEMBL11685688 | 0.69 | ALDH1A1 (0.41) | KDM4EGAASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL949738 | 0.69 | MEN1 (0.52) | KDM4EMAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL13763209 | 0.68 | PIK3CG (0.56) | KDM4EGAAMAPTPOLBMAPK1 | |
| SCHEMBL15943680 | 0.68 | IDO1 (0.49) | TDP1KDM4EGAAMAPTPKM | |
| Hydrochloric Acid SCHEMBL10861172 | 0.67 | ACHE (0.55) | TDP1LMNACYP3A4ACHECYP1A2 | |
| SCHEMBL10860459 | 0.67 | ALDH1A1 (0.53) | TDP1KDM4EGAAMAPTPKM | |
| SCHEMBL8465810 | 0.67 | MEN1 (0.57) | KDM4EMAPTPOLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371074-A | Use of saccharin derivatives as proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-12-06 | — | — | US | claimed |
| EP-0542372-A1 | 2-Substituted saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-05-19 | — | — | EP | claimed |