Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310025 | 0.82 | PKM (0.44) | ALDH1A1PKMLMNAKMT2AKDM4E | |
| SCHEMBL7315475 | 0.81 | PKM (0.44) | ALDH1A1PKMLMNAKMT2AKDM4E | |
| SCHEMBL7308723 | 0.79 | PKM (0.43) | ALDH1A1PKMLMNAKMT2AHTT | |
| SCHEMBL7309351 | 0.78 | PDE3B (0.59) | PPARAALDH1A1PKMLMNAKMT2A | |
| SCHEMBL7309366 | 0.75 | HSD11B1 (0.44) | ALDH1A1KMT2AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL7309349 | 0.75 | PDE3B (0.41) | PPARAALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL7316070 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2AKDM4EHTT | |
| SCHEMBL7309122 | 0.73 | KCNA5 (0.49) | ALDH1A1PKMLMNAKMT2AHTT | |
| SCHEMBL10285854 | 0.73 | KDM4E (0.65) | PPARAALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL7309989 | 0.72 | MAOA (0.64) | ALDH1A1LMNAKMT2ACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |