Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320279 | 0.86 | BIRC2 (0.76) | BIRC2ALDH1A1 | |
| SCHEMBL7321252 | 0.84 | BIRC2 (0.62) | BIRC2 | |
| SCHEMBL7313729 | 0.84 | BIRC2 (0.62) | BIRC2 | |
| SCHEMBL7323329 | 0.84 | BIRC2 (0.53) | BIRC2ALDH1A1 | |
| SCHEMBL7320818 | 0.80 | BIRC2 (0.69) | BIRC2ALDH1A1 | |
| SCHEMBL7314484 | 0.78 | KMO (0.57) | CA1CA12CA2CA9 | |
| SCHEMBL7317378 | 0.77 | CA2 (0.45) | CA1CA12CA2CA9 | |
| SCHEMBL7317352 | 0.77 | CA2 (0.45) | CA1CA12CA2CA9 | |
| SCHEMBL7317343 | 0.77 | CA2 (0.45) | CA1CA12CA2CA9 | |
| SCHEMBL7321398 | 0.77 | MME (0.71) | BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |