Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310436 | 0.84 | BIRC2 (0.61) | BIRC2ALDH1A1 | |
| SCHEMBL7320279 | 0.80 | BIRC2 (0.76) | BIRC2ALDH1A1KMT2A | |
| SCHEMBL7314012 | 0.80 | ALDH1A1 (0.51) | MAPK1NPC1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7314006 | 0.80 | ALDH1A1 (0.51) | MAPK1NPC1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7314034 | 0.80 | ALDH1A1 (0.51) | MAPK1NPC1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7323337 | 0.79 | MAPK1 (0.49) | MAPK1NPC1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7314023 | 0.79 | MEN1 (0.50) | MAPK1NPC1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7313729 | 0.78 | BIRC2 (0.62) | BIRC2USP2 | |
| SCHEMBL7321252 | 0.78 | BIRC2 (0.62) | BIRC2USP2 | |
| SCHEMBL7320818 | 0.74 | BIRC2 (0.69) | BIRC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |