Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 6/20 | 0.42 |
| ▸ | THRA | P10827 | 5/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311442 | 0.85 | NPC1 (0.43) | RAB9ANPC1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL7308962 | 0.84 | HPGD (0.42) | RAB9ANPC1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL7317901 | 0.76 | ALDH1A1 (0.44) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7310719 | 0.75 | THRA (0.42) | RAB9ANPC1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL7321082 | 0.71 | THRA (0.47) | THRBTHRACA9ALDH1A1MAPT | |
| SCHEMBL16175317 | 0.70 | MAPT (0.46) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7313197 | 0.70 | THRA (0.36) | HPGDTSHRSMN1; SMN2THRBTHRA | |
| SCHEMBL9117309 | 0.70 | HPGD (0.65) | RAB9ANPC1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL7309225 | 0.69 | THRB (0.47) | RAB9ANPC1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL10374480 | 0.67 | SIRT5 (0.43) | HPGDSMN1; SMN2THRBTHRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |