Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.43 |
| ▸ | MMP13 | P45452 | 11/20 | 0.43 |
| ▸ | MMP3 | P08254 | 10/20 | 0.43 |
| ▸ | MMP9 | P14780 | 9/20 | 0.43 |
| ▸ | MMP1 | P03956 | 7/20 | 0.43 |
| ▸ | MMP8 | P22894 | 6/20 | 0.43 |
| ▸ | MMP12 | P39900 | 6/20 | 0.42 |
| ▸ | MMP14 | P50281 | 5/20 | 0.42 |
| ▸ | MMP16 | P51512 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320215 | 0.92 | MMP2 (0.45) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7321501 | 0.91 | MMP3 (0.50) | MMP2MMP13MMP3MMP9MMP1 | |
| Biphenyl SCHEMBL7313998 | 0.82 | TP53 (0.42) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7317781 | 0.78 | RAPGEF4 (0.47) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7324791 | 0.77 | MMP1 (0.39) | MMP2MMP13MMP3MMP9MMP1 | |
| Biphenyl SCHEMBL7320212 | 0.75 | MMP2 (0.45) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7319427 | 0.75 | RAPGEF4 (0.44) | MMP2MMP13MMP3MMP9MMP1 | |
| Biphenyl SCHEMBL7321499 | 0.74 | MMP9 (0.50) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7324085 | 0.74 | HTT (0.43) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7317410 | 0.73 | ALDH1A1 (0.47) | MMP2MMP13MMP3MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |