Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | BAX | Q07812 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451346 | 0.80 | LTA4H (0.55) | LTA4HTSHRMAOBKDM4EGLA | |
| SCHEMBL8166466 | 0.77 | LTA4H (0.35) | LTA4HTSHRMAOBKDM4EGLA | |
| SCHEMBL7312733 | 0.75 | SMN1; SMN2 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL6003349 | 0.74 | LTA4H (0.48) | LTA4HTSHRMAOBKDM4EGLA | |
| SCHEMBL10337545 | 0.72 | LTA4H (0.46) | LTA4HTSHRMAOBKDM4EGLA | |
| SCHEMBL11612858 | 0.72 | TRPA1 (0.36) | TSHRTRPA1ALDH1A1 | |
| SCHEMBL7313642 | 0.72 | NQO1 (0.33) | LTA4HALDH1A1 | |
| SCHEMBL7307448 | 0.72 | PGR (0.35) | MAPTALDH1A1PGRHDAC8 | |
| SCHEMBL6845975 | 0.71 | MAOA (0.50) | LTA4HTSHRMAOBKDM4EGLA | |
| SCHEMBL18274775 | 0.71 | LTA4H (0.50) | LTA4HTSHRMAOBKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634396-B1 | Amino acid derivatives and their use as inhibitors of encephalinase | BIOPROJET SOC CIV (FR) | 1998-10-28 | — | — | EP | disclosed |
| EP-0634396-A1 | Amino acid derivatives and their use as inhibitors of encephalinase | SOCIETE CIVILE BIOPROJET (FR) | 1995-01-18 | — | — | EP | disclosed |