Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314634 | 0.91 | GLA (0.38) | ALOX15TRPV6HTR7KDM1AKDM4E | |
| SCHEMBL7309061 | 0.91 | HSD17B10 (0.35) | HSD17B10KDM4EALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL7313428 | 0.89 | CYP1A2 (0.37) | HTR7KDM1ASMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL7313193 | 0.89 | SIGMAR1 (0.33) | TRPV6HTR7KDM1ASIGMAR1SMN1; SMN2 | |
| SCHEMBL7316047 | 0.88 | GRIN1 (0.42) | HTR7SIGMAR1CHRM2CHRM1 | |
| SCHEMBL7307155 | 0.86 | ITGB3 (0.34) | ITGB3ITGA2BALOX15TRPV6HTR7 | |
| SCHEMBL7315123 | 0.84 | HTR7 (0.38) | ALOX15HTR7HSD17B10KDM4EALDH1A1 | |
| SCHEMBL7303939 | 0.84 | SMN1; SMN2 (0.44) | ALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL7305000 | 0.83 | CHRM2 (0.36) | ITGB3ITGA2BALOX15HTR7HSD17B10 | |
| SCHEMBL7316521 | 0.83 | SMN1; SMN2 (0.41) | HTR7HSD17B10KDM1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |