Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305000 | 0.93 | CHRM2 (0.36) | ITGB3ITGA2BALOX15NPY1RCHRM2 | |
| SCHEMBL7344820 | 0.91 | HRH1 (0.32) | HRH1CHRM2CHRM1HTR7 | |
| SCHEMBL7305674 | 0.90 | S1PR5 (0.33) | NPY1RHRH1CHRM2CHRM4CHRM5 | |
| SCHEMBL7343679 | 0.90 | OPRM1 (0.33) | — | |
| SCHEMBL7319402 | 0.89 | SIGMAR1 (0.35) | NPY1RCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7315123 | 0.88 | HTR7 (0.38) | ALOX15CHRM2CHRM1HTR7 | |
| SCHEMBL7306204 | 0.86 | ITGB3 (0.38) | ITGB3ITGA2BALOX15TRPV6CHRM2 | |
| SCHEMBL7316047 | 0.86 | GRIN1 (0.42) | CHRM2CHRM1HTR7 | |
| SCHEMBL7304991 | 0.85 | ACHE (0.47) | CHRM4 | |
| SCHEMBL7315805 | 0.85 | SMN1; SMN2 (0.35) | CHRM2CHRM1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |