Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308198 | 0.87 | ALDH1A1 (0.34) | ALDH1A1LMNAALOX12THRATHRB | |
| SCHEMBL7315888 | 0.80 | TDP1 (0.38) | SIRT3THRATHRB | |
| SCHEMBL10376742 | 0.75 | SIRT5 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL7314747 | 0.71 | SIGMAR1 (0.38) | SIRT3ALDH1A1LMNAKDM4E | |
| SCHEMBL7319714 | 0.68 | PDE3B (0.54) | — | |
| SCHEMBL10375883 | 0.68 | SIRT5 (0.37) | ALDH1A1KDM4E | |
| SCHEMBL7307676 | 0.67 | PDE3B (0.55) | — | |
| SCHEMBL7320170 | 0.67 | KMT2A (0.37) | SIRT3ALDH1A1LMNAKDM4E | |
| SCHEMBL19548246 | 0.66 | MAPT (0.43) | SIRT3ALDH1A1LMNAKDM4E | |
| SCHEMBL7310447 | 0.66 | PDE3B (0.55) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |