Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315237 | 0.84 | SIGMAR1 (0.39) | SIGMAR1BACE1SCN9AKMT2AALDH1A1 | |
| SCHEMBL7315888 | 0.80 | TDP1 (0.38) | SCN9AKMT2ASIRT3MEN1SMN1; SMN2 | |
| SCHEMBL7320170 | 0.79 | KMT2A (0.37) | SIGMAR1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL7317566 | 0.78 | THRB (0.44) | KMT2AALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL7315902 | 0.76 | HTR7 (0.34) | KMT2AALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL7312450 | 0.73 | LMNA (0.44) | KMT2AALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL7315879 | 0.71 | SIRT3 (0.36) | ALDH1A1LMNASIRT3KDM4E | |
| SCHEMBL10375971 | 0.71 | HPGD (0.44) | KMT2AALDH1A1MEN1HPGDTSHR | |
| SCHEMBL26369296 | 0.69 | TSHR (0.49) | KMT2AALDH1A1MAPTLMNASIRT3 | |
| SCHEMBL7310447 | 0.69 | PDE3B (0.55) | KMT2AALDH1A1MEN1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |