Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323050 | 0.82 | HRH3 (0.53) | ALDH1A1HRH3MAPTMEN1KMT2A | |
| SCHEMBL7322549 | 0.81 | SIGMAR1 (0.48) | ALDH1A1HRH3MAPTMEN1KMT2A | |
| SCHEMBL27466037 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GAAHRH3MEN1KMT2A | |
| SCHEMBL7325823 | 0.78 | SIGMAR1 (0.47) | ALDH1A1HRH3MAPTMEN1KMT2A | |
| SCHEMBL7319063 | 0.78 | HRH3 (0.44) | ALDH1A1HRH3MAPTMEN1KMT2A | |
| SCHEMBL7322205 | 0.77 | DRD2 (0.43) | ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL7323813 | 0.77 | SIGMAR1 (0.46) | ALDH1A1HRH3MAPTMEN1KMT2A | |
| SCHEMBL7323139 | 0.76 | HRH3 (0.42) | ALDH1A1HRH3MAPTMEN1KMT2A | |
| SCHEMBL7312887 | 0.76 | FFAR1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL7315858 | 0.74 | FFAR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154483-C | Use of amines to produce drugs for preventing tumour cell proliferation | ��ŵ��-ʥ�������ɷ�����˾ | 2004-06-23 | — | — | CN | disclosed |
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |
| CN-1226825-A | Use of amines to produce drugs for preventing tumour cell proliferation | SANOFI SA (FR) | 1999-08-25 | — | — | CN | disclosed |