Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323813 | 0.91 | SIGMAR1 (0.46) | SIGMAR1APPMEN1KMT2AHRH3 | |
| SCHEMBL7323050 | 0.87 | HRH3 (0.53) | SIGMAR1MEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL7322549 | 0.84 | SIGMAR1 (0.48) | SIGMAR1APPMEN1KMT2AHRH3 | |
| SCHEMBL7319063 | 0.81 | HRH3 (0.44) | SIGMAR1MEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL7323873 | 0.79 | ALDH1A1 (0.46) | SIGMAR1ALDH1A1MAPT | |
| SCHEMBL7323139 | 0.79 | HRH3 (0.42) | SIGMAR1MEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL7316201 | 0.78 | ALDH1A1 (0.47) | SIGMAR1MEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL7312887 | 0.76 | FFAR1 (0.44) | — | |
| SCHEMBL7323035 | 0.75 | SLC6A4 (0.43) | APPMEN1KMT2APKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7315858 | 0.75 | FFAR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |