Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314478 | 0.87 | HTR1A (0.47) | HPGDALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL5446276 | 0.80 | L3MBTL1 (0.53) | MAOBALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3813849 | 0.80 | PTGER1 (0.54) | MAOBHPGDALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7323366 | 0.80 | KMT2A (0.46) | S1PR5HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL9840655 | 0.77 | L3MBTL1 (0.49) | S1PR1S1PR5PRKXACVR1MAOB | |
| SCHEMBL862827 | 0.75 | NR4A1 (0.57) | NAAAMAOBFAAHALDH1A1NPC1 | |
| SCHEMBL2450503 | 0.75 | KMT2A (0.57) | HPGDALDH1A1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL20954694 | 0.75 | MTNR1A (0.48) | MAOBHPGDALDH1A1NPC1NFKB1 | |
| SCHEMBL6247717 | 0.74 | MAOB (0.60) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3023243 | 0.74 | MAOB (0.51) | MAOBL3MBTL1NR4A2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218000-A | Nervous system disorders, antiischemic agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1993-06-08 | — | — | US | disclosed |
| EP-0361687-A1 | Therapeutic polyamine-amides | BTG INTERNATIONAL LIMITED (GB) | 1990-04-04 | — | — | EP | disclosed |
| EP-0360437-A1 | Biocidal polylamine-amides | BTG INTERNATIONAL LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |
| WO-1990001875-A1 | BIOCIDAL POLYAMINE-AMIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-03-08 | — | — | WO | disclosed |
| WO-1990002114-A1 | THERAPEUTIC POLYAMINE-AMIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-03-08 | — | — | WO | disclosed |