Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314478 | 0.82 | HTR1A (0.47) | KMT2AMEN1MAPK1FOLH1MAPT | |
| SCHEMBL2450503 | 0.81 | KMT2A (0.57) | KMT2AMAPK1PKMHPGDALDH1A1 | |
| SCHEMBL9774160 | 0.80 | ALDH1A1 (0.65) | KMT2AMEN1MAPK1FFAR1NPC1 | |
| SCHEMBL7318012 | 0.80 | NAAA (0.44) | KMT2ANPC1RAB9AHSD17B10HPGD | |
| SCHEMBL19658177 | 0.79 | KMT2A (0.50) | KMT2AMAPK1PKMPOLBHPGD | |
| SCHEMBL26851429 | 0.79 | MTNR1A (0.55) | KMT2AMEN1NPC1RAB9APKM | |
| SCHEMBL3817639 | 0.78 | FFAR4 (0.55) | FFAR1NPC1RAB9AFOLH1SLC2A1 | |
| SCHEMBL7384707 | 0.78 | HTT (0.51) | KMT2AMEN1NPC1PKMMAPT | |
| SCHEMBL31225579 | 0.78 | FAAH (0.53) | KMT2AMAPK1RAB9APKMHPGD | |
| SCHEMBL31225984 | 0.77 | KMT2A (0.46) | KMT2AMAPK1PKMHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218000-A | Nervous system disorders, antiischemic agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1993-06-08 | — | — | US | disclosed |
| EP-0361687-A1 | Therapeutic polyamine-amides | BTG INTERNATIONAL LIMITED (GB) | 1990-04-04 | — | — | EP | disclosed |
| EP-0360437-A1 | Biocidal polylamine-amides | BTG INTERNATIONAL LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |
| WO-1990001875-A1 | BIOCIDAL POLYAMINE-AMIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-03-08 | — | — | WO | disclosed |
| WO-1990002114-A1 | THERAPEUTIC POLYAMINE-AMIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-03-08 | — | — | WO | disclosed |