Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310810 | 0.83 | THRA (0.40) | THRATHRBBCHEACHEL3MBTL1 | |
| SCHEMBL7313337 | 0.82 | BCHE (0.40) | THRATHRBBCHEACHEL3MBTL1 | |
| SCHEMBL7316914 | 0.79 | THRA (0.46) | THRATHRBBCHEACHEL3MBTL1 | |
| SCHEMBL7319695 | 0.73 | ALDH1A1 (0.46) | THRATHRBBCHEACHEL3MBTL1 | |
| SCHEMBL7307955 | 0.70 | L3MBTL1 (0.43) | THRATHRBBCHEACHEL3MBTL1 | |
| SCHEMBL7316157 | 0.69 | PDE3B (0.40) | ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL10377089 | 0.69 | SIRT5 (0.43) | BCHEACHEALDH1A1KDM4EHPGD | |
| SCHEMBL7309552 | 0.69 | THRA (0.41) | THRATHRBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7320520 | 0.68 | PDE3B (0.47) | ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL14334111 | 0.68 | PDK1 (0.43) | ACHEL3MBTL1ALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |