Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319630 | 0.90 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2MAPK1RAB9A | |
| SCHEMBL7361622 | 0.88 | ALDH1A1 (0.56) | ALDH1A1LMNAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL7331816 | 0.83 | SNCA (0.52) | ALDH1A1LMNASMN1; SMN2RAB9AMAPT | |
| SCHEMBL7324191 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1LMNASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL7328793 | 0.79 | L3MBTL1 (0.47) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7328071 | 0.78 | RXFP1 (0.45) | ALDH1A1MAPK1NPC1RAB9AMAPT | |
| SCHEMBL7319642 | 0.76 | SMN1; SMN2 (0.42) | ALDH1A1LMNASMN1; SMN2MAPK1RAB9A | |
| SCHEMBL10357380 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL7319626 | 0.75 | ALDH1A1 (0.48) | ALDH1A1LMNAKMT2A | |
| SCHEMBL8470246 | 0.75 | CES2 (0.45) | ALDH1A1LMNASMN1; SMN2MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |